Stanford University Mass Spectrometry's 2022 Research Applications Symposium will transport scientists from around the world for a virtual visit with Stanford's mass spectrometry community, sharing our exciting campus research and resources. See below for the full lineup of speakers.
Today we are spotlighting Dr. Ruth Huttenhain, who will soon be joining the Stanford faculty in the Dept. of Molecular & Cellular Physiology. Her talk is titled, "Mapping the diversity in spatiotemporal regulation of G protein-coupled receptors" (view talk abstract here).
Ruth obtained her Ph.D. in Systems Biology from ETH Zurich, Switzerland, where she worked with Ruedi Aebersold, Ph.D., to develop a novel, targeted proteomics strategy for sensitive and reproducible quantification of proteins across large sample cohorts. Supported by the Swiss National Science and the Human Frontiers Science Foundation, Ruth performed her postdoctoral work with Nevan Krogan, Ph.D., at the University of California, San Francisco (UCSF). During her postdoc, Ruth studied protein network dynamics in the context of HIV infection, which led to the discovery of the ARIH2 as a novel HIV-dependency factor. She also pioneered the first proteomics approach that can resolve protein interaction networks simultaneously with temporal and spatial resolution. Applying this approach to study dynamics of protein networks engaged by ligand-activated GPCRs led to the discovery of a previously unrecognized ubiquitin network regulating opioid receptor function. After her postdoc Ruth continued at UCSF as an Assistant Adjunct Professor with a research focus on how GPCRs decode extracellular cues into dynamic and context-specific cellular signaling networks to elicit diverse physiologic responses, a research direction that she will further explore in her lab at Stanford. She will exploit quantitative proteomics to capture the spatiotemporal organization of GPCR signaling networks combined with functional genomics to study their impact on physiology.
SUMS-RAS 2022 Speakers:
Dr. Yuqin Dai, Director, ChEM-H Metabolomics Knowledge Center, Stanford University
Dr. Ruth Huttenhain, Incoming Assistant Professor, Dept. of Molecular & Cellular Physiology, Stanford University
Dr. Christie Jilly-Rehak, Research Scientist/Lab Manager, SHRIMP-RG Lab, Stanford University
Dr. Chris Lock, Clinical Associate Professor, Dept. of Neurology & Neurological Sciences, Stanford University
Dr. Parag Mallick, Associate Professor, Dept. of Radiology, Stanford University
Dr. Sharon Pitteri, Associate Professor, Dept. of Radiology, Stanford University
Dr. Karrie Weaver, Technical Director, SIGMA Lab Facility, Stanford University
Dr. Shou-Ling Xu, Research Scientist, Plant Biology, Carnegie Institution for Science
Commander-Level Sponsors:
Ensign-Level Sponsors:
Allis Chien, Ph.D. Director, Stanford University Mass Spectrometry
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