All Members Community

 View Only
  • 1.  Seeking service for small molecule purification

    Posted 5 days ago

    Fellow ABRF members,

        A former client of my bioanalytical core lab is looking for a service lab that can provide preparative separation of two closely related small molecules (400 & 472 Da). I am fully retired and no longer have the lab resources that he needs. His team has identified two biologically active molecules. They believe that separation might be accomplished using preparative ion exchange chromatography. I was unable to find a suitable service lab in the Core Marketplace. Please reply if you can recommend a lab that might be able to help my colleague. 

    Mark Lively

    ABRF Past President (2001-2002)



    ------------------------------
    Mark Lively
    Professor Emeritus
    Wake Forest University School of Medicine
    Winston-Salem NC
    ------------------------------


  • 2.  RE: Seeking service for small molecule purification

    Posted 4 days ago

    Hi Mark,

    Depending on the chemical nature of the molecules, one of two cores at my institution may have the resources to assist your client

    1. Macromolecular Therapeutics Development Facility (MTDF). Contact: Scott J. Garforth, Ph.D. (Operations Director), 718-678-1146, scott.garforth@einsteinmed.edu
    2. Chemical Synthesis Core. Contact: Peter Bellotti, Ph.D. (Operations Director), 718.430.4005, peter.bellotti@einsteinmed.edu


    ------------------------------
    Larry Leung
    Immune Monitoring Core Facility
    Albert Einstein College of Medicine
    Bronx, NY
    ------------------------------



  • 3.  RE: Seeking service for small molecule purification

    Posted 7 hours ago

    Hi Mark,

    The University of Pittsburgh's Small Molecule Biomarker Core might be able to help, but they would need more information. Please have them reach out to Raymond West, PhD (Assistant Director), rew82@pitt.edu or (412) 648-9854.

    Best,

    Ashley Zyhowski



    ------------------------------
    Ashley Zyhowski
    Research Resources Coordinator
    Office of Research, Health Sciences
    University iLab Administrator
    University of Pittsburgh
    ------------------------------